ICD-10-CM › D50-D89 › D80-D89 › D81 Combined immunodeficiencies › D81.5
Purine nucleoside phosphorylase [PNP] deficiency
ValidICD-10-CM diagnosis code.
Valid for claims with a date of service in the current code year.
What has happened to this code
Every change the publisher made, from 2007 to now. Entries marked draft are from the pre-implementation releases: ICD-10 took effect on 1 October 2015, so nothing before FY2016 was ever valid on a claim.
- FY2007 Added to the draft code set draft Purine nucleoside phosphorylase [PNP] deficiency
Official coding rules
Published by CDC for FY2027. A rule attached to a category binds every code beneath it, so the rules inherited from this code's ancestors are shown with the code they come from.
Inherited from D81 Combined immunodeficiencies
Excludes1 - never coded here
- autosomal recessive agammaglobulinemia (Swiss type) (D80.0)
Inherited from the D80-D89 section Certain disorders involving the immune mechanism (D80-D89)
Excludes1 - never coded here
- autoimmune disease (systemic) NOS (M35.9)
- functional disorders of polymorphonuclear neutrophils (D71-)
Excludes2 - not included here
- human immunodeficiency virus [HIV] disease (B20)
Includes
- defects in the complement system
- immunodeficiency disorders, except human immunodeficiency virus [HIV] disease
- sarcoidosis
How CDC's index refers to this code
Wording from the official alphabetic index. Much of it appears nowhere in the code description, which is why a search for the everyday phrase so often finds nothing.
- Deficit
- Avitaminosis
- Hypovitaminosis
- Vitamin deficiency
- Leukoencephalopathy
- Deprivation > vitamins
- Deficiency, deficient > factor
- Defect, defective > coagulation
- Deficiency, deficient > clotting
- Disturbance > absorption > vitamin
- Encephalopathy > in > lack of vitamin
- Deficiency, deficient > clotting factor NEC
- Deficiency, deficient > coagulation NOS > clotting factor NEC
- Deficiency, deficient > purine nucleoside phosphorylase
Codes in the same group
| Code | Description | Status |
|---|---|---|
| D81.0 | Severe combined immunodeficiency [SCID] with reticular dysgenesis | Valid |
| D81.1 | Severe combined immunodeficiency [SCID] with low T- and B-cell numbers | Valid |
| D81.2 | Severe combined immunodeficiency [SCID] with low or normal B-cell numbers | Valid |
| D81.3 | Adenosine deaminase [ADA] deficiency | Not billable |
| D81.4 | Nezelof's syndrome | Valid |
| D81.6 | Major histocompatibility complex class I deficiency | Valid |
| D81.7 | Major histocompatibility complex class II deficiency | Valid |
| D81.8 | Other combined immunodeficiencies | Not billable |
| D81.9 | Combined immunodeficiency, unspecified | Valid |