Activated Phosphoinositide 3-kinase Delta Syndrome [APDS]

ValidICD-10-CM diagnosis code.

Valid for claims with a date of service in the current code year.

Valid FY2023 onwards.

What has happened to this code

Every change the publisher made, from 2023 to now.

FY2023 Added to the code set Activated Phosphoinositide 3-kinase Delta Syndrome [APDS]

Official coding rules

Published by CDC for FY2027. A rule attached to a category binds every code beneath it, so the rules inherited from this code's ancestors are shown with the code they come from.

Inherited from D81 Combined immunodeficiencies

Excludes1 - never coded here

autosomal recessive agammaglobulinemia (Swiss type) (D80.0)

Inherited from the D80-D89 section Certain disorders involving the immune mechanism (D80-D89)

Excludes1 - never coded here

autoimmune disease (systemic) NOS (M35.9)
functional disorders of polymorphonuclear neutrophils (D71-)

Excludes2 - not included here

human immunodeficiency virus [HIV] disease (B20)

Includes

defects in the complement system
immunodeficiency disorders, except human immunodeficiency virus [HIV] disease
sarcoidosis

How CDC's index refers to this code

Wording from the official alphabetic index. Much of it appears nowhere in the code description, which is why a search for the everyday phrase so often finds nothing.

Syndrome > activated phosphoinositide 3-kinase delta syndrome [APDS]
Disease, diseased > p110d-activating mutation causing senescent T cells, lymphadenopathy, and immunodeficiency [PASLI]

Codes in the same group

Code	Description	Status
D81.81	Biotin-dependent carboxylase deficiency	Not billable
D81.89	Other combined immunodeficiencies	Valid