ICD-10-CM › D50-D89 › D80-D89 › D81.81 Biotin-dependent carboxylase deficiency › D81.819

Valid for claims with a date of service in the current code year.

Valid FY2016 onwards.

What has happened to this code

Official coding rules

Published by CDC for FY2027. A rule attached to a category binds every code beneath it, so the rules inherited from this code's ancestors are shown with the code they come from.

Inherited from D81 Combined immunodeficiencies

Excludes1 - never coded here

• autosomal recessive agammaglobulinemia (Swiss type) (D80.0)

Inherited from the D80-D89 section Certain disorders involving the immune mechanism (D80-D89)

Excludes1 - never coded here

• autoimmune disease (systemic) NOS (M35.9)
• functional disorders of polymorphonuclear neutrophils (D71-)

Excludes2 - not included here

• human immunodeficiency virus [HIV] disease (B20)

Includes

• defects in the complement system
• immunodeficiency disorders, except human immunodeficiency virus [HIV] disease
• sarcoidosis

How CDC's index refers to this code

Wording from the official alphabetic index. Much of it appears nowhere in the code description, which is why a search for the everyday phrase so often finds nothing.

• Deficit
• Avitaminosis
• Hypovitaminosis
• Vitamin deficiency
• Leukoencephalopathy
• Deprivation > vitamins
• Deficiency, deficient > factor
• Deficiency, deficient > immuno
• Defect, defective > coagulation
• Deficiency, deficient > clotting
• Disturbance > absorption > vitamin
• Encephalopathy > in > lack of vitamin
• Deficiency, deficient > clotting factor NEC
• Deficiency, deficient > coagulation NOS > clotting factor NEC
• Deficiency, deficient > biotin-dependent carboxylase
• Immunodeficiency > combined > biotin-dependent carboxylase

Codes in the same group

Code	Description	Status
D81.810	Biotinidase deficiency	Valid
D81.818	Other biotin-dependent carboxylase deficiency	Valid