ICD-10-CM › E00-E89 › E70-E88 › E72.1 Disorders of sulfur-bearing... › E72.12
Methylenetetrahydrofolate reductase deficiency
ValidICD-10-CM diagnosis code.
Valid for claims with a date of service in the current code year.
What has happened to this code
Every change the publisher made, from 2007 to now. Entries marked draft are from the pre-implementation releases: ICD-10 took effect on 1 October 2015, so nothing before FY2016 was ever valid on a claim.
- FY2007 Added to the draft code set draft Methylenetetrahydrofolate reductase deficiency
Official coding rules
Published by CDC for FY2027. A rule attached to a category binds every code beneath it, so the rules inherited from this code's ancestors are shown with the code they come from.
Inherited from E72 Other disorders of amino-acid metabolism
Excludes1 - never coded here
- disorders of:
- aromatic amino-acid metabolism (E70.-)
- branched-chain amino-acid metabolism (E71.0-E71.2)
- fatty-acid metabolism (E71.3)
- purine and pyrimidine metabolism (E79.-)
- gout (M1A.-, M10.-)
Inherited from the E70-E88 section Metabolic disorders (E70-E88)
Excludes1 - never coded here
- androgen insensitivity syndrome (E34.5-)
- congenital adrenal hyperplasia (E25.0)
- hemolytic anemias attributable to enzyme disorders (D55.-)
- Marfan syndrome (Q87.4-)
- 5-alpha-reductase deficiency (E29.1)
Excludes2 - not included here
- Ehlers-Danlos syndromes (Q79.6-)
How CDC's index refers to this code
Wording from the official alphabetic index. Much of it appears nowhere in the code description, which is why a search for the everyday phrase so often finds nothing.
- Deficit
- Avitaminosis
- Hypovitaminosis
- Vitamin deficiency
- Leukoencephalopathy
- Deprivation > vitamins
- Deficiency, deficient > factor
- Defect, defective > coagulation
- Deficiency, deficient > clotting
- Disturbance > absorption > vitamin
- Encephalopathy > in > lack of vitamin
- Deficiency, deficient > clotting factor NEC
- Deficiency, deficient > coagulation NOS > clotting factor NEC
- Deficiency, deficient > methylenetetrahydrofolate reductase
- Disorder > metabolism NOS > amino-acid > sulfur-bearing > methylenetetrahydrofolate reductase deficiency
Codes in the same group
| Code | Description | Status |
|---|---|---|
| E72.10 | Disorders of sulfur-bearing amino-acid metabolism, unspecified | Valid |
| E72.11 | Homocystinuria | Valid |
| E72.19 | Other disorders of sulfur-bearing amino-acid metabolism | Valid |