ICD-10-CM › D50-D89 › D80-D89 › D89 Other disorders involving the... › D89.4

D89.4

Mast cell activation syndrome and related disorders

Not billableICD-10-CM diagnosis code.

This code exists but cannot be submitted on its own. It groups the more specific codes beneath it.

A category header for its whole life, FY2017 onwards. It has never been valid for submission on its own.

Submit one of these 6 more specific codes instead:

  • D89.40 Mast cell activation, unspecified
  • D89.41 Monoclonal mast cell activation syndrome
  • D89.42 Idiopathic mast cell activation syndrome
  • D89.43 Secondary mast cell activation
  • D89.44 Hereditary alpha tryptasemia
  • D89.49 Other mast cell activation disorder

What has happened to this code

Every change the publisher made, from 2017 to now.

  1. FY2017 Added to the code set Mast cell activation syndrome and related disorders

Official coding rules

Published by CDC for FY2027. A rule attached to a category binds every code beneath it, so the rules inherited from this code's ancestors are shown with the code they come from.

Inherited from D89 Other disorders involving the immune mechanism, not elsewhere classified

Excludes1 - never coded here

  • hyperglobulinemia NOS (R77.1)
  • monoclonal gammopathy (of undetermined significance) (D47.2)

Excludes2 - not included here

  • transplant failure and rejection (T86.-)

Inherited from the D80-D89 section Certain disorders involving the immune mechanism (D80-D89)

Excludes1 - never coded here

  • autoimmune disease (systemic) NOS (M35.9)
  • functional disorders of polymorphonuclear neutrophils (D71-)

Excludes2 - not included here

  • human immunodeficiency virus [HIV] disease (B20)

Includes

  • defects in the complement system
  • immunodeficiency disorders, except human immunodeficiency virus [HIV] disease
  • sarcoidosis

Codes in the same group

CodeDescriptionStatus
D89.0 Polyclonal hypergammaglobulinemia Valid
D89.1 Cryoglobulinemia Valid
D89.2 Hypergammaglobulinemia, unspecified Valid
D89.3 Immune reconstitution syndrome Valid
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified Not billable
D89.9 Disorder involving the immune mechanism, unspecified Valid